Archives of Clinical and Biomedical Research

ISSN

2572-5017

Abstracting and Indexing



Indexing

 

Abstract

The Effects of Severe Iron Deficiency Anemia on T-wave Intervals

Aim: Changes in the iron level in the myocardium may be affected by sodium and potassium channels in myocytes and there may be a contribution to the etiology of cardiac arrhythmia. The aim of this study was to examine for the first time in literature how the Tp-e interval, which has been accepted in recent years as a strong ventricular repolarisation index, is affected in female patients with severe iron deficiency anemia.

Material and Methods:
The study included a total of 64 participants, as a study group of 34 patients diagnosed with severe iron deficiency anemia (Hgb<8g/dL Ferritin<14 mcg/L, MCV<80 mm3) and a control group of 34 subjects. To determine the QTc and Tp-Te interval durations, manual examination was made of manual precordial V5 lead ECGs taken routinely on the presentation of all participants.

Results: The Tp-e interval was determined to be statistically significantly shorter in the patients (78.97 ± 8.63 ms) compared to the control group (84.57 ± 10.13 ms) (p<0.05). A positive relationship was determined between Tp-e and QTc durations and Hgb and ferritin levels (p<0.05).

Conclusion: The results of the study showed that the QTc duration and the Tp-e duration were shorter in female patients with iron deficiency anemia, and therefore iron deficiency anemia can be discounted as a cause of prolonged QTc and Tp-e durations.

Author(s):

Huseyin Avni Findikli, Ayse Sahin Tutak

Abstract PDF
Announcements

Submit Article to Us

Manuscript

In Association With

TBRSI

Fortune Journals follows COPE Guidelines

COPE

Fortune Journals submit each review to Publons

Publons